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Sodium salicylate

 

Sodium salicylate (CAS 54-21-7) is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxide under higher temperature and pressure. Historically, it has been synthesized from methyl salicylate (found in wintergreen plants or the bark of sweet birch tree) by reacting it with an excess of sodium hydroxide and heating it under reflux.


Application

It is used in medicine as an analgesic and antipyretic. 

Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells  and also necrosis.
It is also a potential replacement for aspirin for people sensitive to it. 
It may also be used as a phosphor for the detection of vacuum ultraviolet radiation and electrons


Packing

25kg bag/fiber drum.

 

Test   items

Specifications

Characters

A white, or almost white crystalline   powder or small,   colourless crystals or shiny flakes, freely    soluble in water, sparingly soluble in alcohol(96%)

Identification

 

Sample Infrared absorption spectropho-tometry Complies with Sodium salicylate.CRS

Gives the reactions of salicylates.

Gives reaction (b) of sodium

Appearance   of solution

The solution is clear and not more intensely coloured   than reference solution BY6

Acidity

0.01M NaOH not more than 2.0ml is required

Chloride

≤200ppm

NMT200ppm

Sulfate

≤600ppm

NMT 600ppm

Heavy metals

≤20ppm

NMT ppm

Loss on drying

≤0.5%

NMT0.5%

Assay(dried substance)

Contains  C7H5NaO3   99.0% to101.0%

 

 


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